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Leukocyte Common Antigen (LCA) Cocktail 0,1 mL

BC-CM016AK
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Leukocyte Common Antigen (LCA) Cocktail 0,1 mL
Specificity and Comments:
CD45 recognizes an antigen found on lymphoid cells. Most neoplastic B cells and T cells stain positively in leukemia and in non-Hodgkin’s lymphomas; whereas most neoplastic myeloid and erythroid cells are generally negative. It is unreactive with epithelium and connective tissues. The PD7/26 and 2B11antibody was included in the 4th International Workshop and was designated as CD45. It belongs to a LCA family of glycoproteins with molecular weights of 180, 190, 205 and 220. It is well suited for formalin-fixed paraffin-embedded tissues and is used as a pan lymphocyte screener for lymphoma.
 
 
Species Reactivity: Human; others not tested.
 
Clone: PD7/26/16 and 2B11
 
Isotype: IgG1/Kappa
 
Immunogen:
PD7.26.16: Human peripheral blood lymphocyte 2B11: Neoplastic cells from T-cell lymphoma
 
Known Applications: Immunohistochemistry
(formalin-fixed paraffin-embedded tissues)
Positive Control: Tonsil or lymphoma
 
Cellular Localization: Cell membrane
 
Supplied As:
Buffer with protein carrier and preservative
 
Storage and Stability:
Store at 4°C. Antibody is stable for 18 months.
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