Leukocyte Common Antigen (LCA) Cocktail 0,1 mL
Specificity and Comments:
CD45 recognizes an antigen found on lymphoid cells. Most neoplastic B cells and T cells stain positively in leukemia and in non-Hodgkin’s lymphomas; whereas most neoplastic myeloid and erythroid cells are generally negative. It is unreactive with epithelium and connective tissues. The PD7/26 and 2B11antibody was included in the 4th International Workshop and was designated as CD45. It belongs to a LCA family of glycoproteins with molecular weights of 180, 190, 205 and 220. It is well suited for formalin-fixed paraffin-embedded tissues and is used as a pan lymphocyte screener for lymphoma.
Species Reactivity: Human; others not tested.
Clone: PD7/26/16 and 2B11
PD7.26.16: Human peripheral blood lymphocyte 2B11: Neoplastic cells from T-cell lymphoma
Known Applications: Immunohistochemistry
(formalin-fixed paraffin-embedded tissues)
Positive Control: Tonsil or lymphoma
Cellular Localization: Cell membrane
Buffer with protein carrier and preservative
Storage and Stability:
Store at 4°C. Antibody is stable for 18 months.