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Bcl-2a 0,1mL

BC-CM003A
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Bcl-2a 0,1mL
Specificity and Comments:
BIOCARE’s 100/D5 MAb is highly specific to bcl-2a and shows no cross-reaction with bcl-x or bax protein. Expression of bcl-2? oncoprotein has been shown to inhibit the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of bcl-2? protein, whereas the normal or hyperplastic germinal centers are negative.
 
 
 
Species Reactivity:
Human; does not react with mouse and rat.
 
Clone: 100/D51
Isotype: IgG1 / ?
 
Immunogen:
A Synthetic peptide, aa 41-54 (GAAPAPGIFSSQPG-Cys), of human bcl-2 protein. 1
 
Known Applications: Immunohistochemistry (formalin-fixed paraffin-embedded tissues)
 
Positive Control: Follicular lymphomas or tonsil
Cellular Localization: Cell membrane
 
Supplied As:
Buffer with protein carrier and preservative
 
Storage and Stability:
Store at 4°C. Stable for 18 months.
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