Glial Fibrillary Acidic Protein (GFAP) 1,0
Specificity and Comments:
This antibody reacts with human GFAP. It shows no cross-reaction with other
intermediate filaments. Anti-GFAP stains astrocytes, ependymal cells and
corresponding tumors. GFAP is useful for distinguishing neoplasms of astrocytic
origin and is useful n differentiating gliomas from metastatic lesions in the
brain. Neuroblastomas, Schwannomas, as well as extra-CNS tumors are not labeled.
Negative staining has been observed with lymphatic tissue, muscle,
gastrointestinal tract, liver, kidney, pancreas and bladder.
Human, pig, rat, dog and chicken
GFAP isolated from porcine spinal cord
Known Applications: Immunohistochemistry (formalin-fixed paraffin-embedded
Positive Control: Normal brain or astrocytoma
Cellular Localization: Cell membrane
Buffer with protein carrier and preservative
Storage and Stability:
Store at 4°C. Antibody is stable for 18 months.